Advanced Dermatology Care

The #1 steroid-free solution developed by dermatologists to stop itch in 5 minutes.

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Trusted by over 149,000 customers

Recommended by 6,000+ Dermatologists Nationwide

Science-Backed Solutions

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2 oz. Cream Single Tube

2 oz. Cream Single Tube

Our best-selling steroid-free formula! Developed by dermatologists to relieve dry, itchy skin and...

$24.99

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2 oz. Anti-Itch Cream 2 Pack

2 oz. Anti-Itch Cream 2 Pack

Our best-selling steroid-free formula! Developed by dermatologists to relieve dry, itchy skin and...

$47.48

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4 oz. Cream 3 Pack

4 oz. Cream 3 Pack

Our advanced steroid-free formula in a large 4 ounce tube for maximum relief! Developed by dermat...

$107.97

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2 oz. Anti-Itch Cream 3 Pack

2 oz. Anti-Itch Cream 3 Pack

Our best-selling steroid-free formula! Developed by dermatologists to relieve dry, itchy skin and...

$67.47

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4 oz. Cream Single Tube

4 oz. Cream Single Tube

Our advanced steroid-free formula in a large 4 ounce tube for maximum relief! Developed by dermat...

$39.99

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Sale
4 oz. Cream 2 Pack

4 oz. Cream 2 Pack

Our advanced steroid-free formula in a large 4 ounce tube for maximum relief! Developed by dermat...

$75.98

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The Proof is in the Experience

"I have had this itchy psoriasis on my hands for years! I have tried everything, including steroid ointments, (that I don’t want to use). My doctor recommended I try Dermeleve and my itching was gone within minutes, This is THE miracle cure."

Taylor R.

"Nothing helped with my chronic itching until I tried this cream. Seriously... the itching is almost completely gone after 5 years. I've been buying tubes for all my friends and family. Best product EVER!"

Theresa A.

"I have seborrheic dermatitis and have tried everything, from topical steroids to prescriptions. Nothing worked until I found Dermeleve. In a matter of minutes, my scalp itch was completely gone and I had no urge to scratch the rest of the day. I use this religiously every morning and will never go without it."

Cindy A.

"I have had this itchy psoriasis on my hands for years! I have tried everything, including steroid ointments, (that I don’t want to use). My doctor recommended I try Dermeleve and my itching was gone within minutes, This is THE miracle cure."

Taylor R.

"Nothing helped with my chronic itching until I tried this cream. Seriously... the itching is almost completely gone after 5 years. I've been buying tubes for all my friends and family. Best product EVER!"

Theresa A.

"I have seborrheic dermatitis and have tried everything, from topical steroids to prescriptions. Nothing worked until I found Dermeleve. In a matter of minutes, my scalp itch was completely gone and I had no urge to scratch the rest of the day. I use this religiously every morning and will never go without it."

Cindy A.

Science-Backed Ingredients

Developed by dermatologists for fast, 100% steroid-free relief, our skin-healing ingredients are backed by science.

Strontium Mineral Salt

Targets the nerves to suppress the sensation of itch.

Ceramides

Lipid-rich molecules that retain moisture and promote skin regeneration.

Hyaluronic Acid

Increases skin hydration up to 96% and helps heal skin more quickly.

Vitamins C & E

Antioxidants that help repair and protect skin from damage.

Shea Butter

Anti-inflammatory properties soothe and moisturize the skin.

Say Goodbye to Chronic Itch with Dermeleve

Fast, lasting relief. No steroids. No side effects.

Chronic itch can disrupt your sleep, focus, and confidence. Whether it’s triggered by eczema, psoriasis, allergic reactions, or dry, irritated skin, finding relief shouldn’t come with compromise. Dermeleve is a dermatologist-developed, steroid-free itch relief cream designed to calm even the most stubborn itching safely and effectively.

Powered by a patented, science-backed formula, Dermeleve works within minutes to relieve itch, burning, and irritation, helping restore comfort and balance to your skin.

Why Choose Dermeleve

Clinically Proven, Fast-Acting Relief

Experience rapid itch relief that lasts up to 8+ hours. Our formula targets the source of itch to calm irritation and discomfort fast.

100% Steroid-Free & Non-Toxic

Unlike hydrocortisone or prescription steroids, Dermeleve provides powerful results without thinning your skin or causing rebound irritation.

Safe for All Skin Types

Gentle enough for daily use on sensitive, dry, or reactive skin. Hypoallergenic, fragrance-free, and dermatologist-tested for adults and children alike.

Dermatologist-Developed & Tested

Created by a team of dermatologists who specialize in chronic itch and inflammatory skin conditions, ensuring safety and real-world effectiveness.

Healing Support for Chronic Conditions

Provides relief for eczema (atopic dermatitis), contact dermatitis, neuropathic itch, and other persistent skin irritations.

100% Money-Back Guarantee

We stand by every tube of Dermeleve. If you’re not satisfied, we’ll refund your purchase, no questions asked.

What Makes Dermeleve Different

Most anti-itch creams only mask symptoms. Dermeleve penetrates deep to interrupt the itch-scratch cycle at its source, helping reduce inflammation and support skin barrier recovery. Over time, consistent use helps restore healthier, more resilient skin.

Patented delivery system for faster absorption

Clinically validated ingredients that soothe and protect

Long-lasting relief that helps break the cycle of chronic itch

Real Relief. Real Results.

Thousands have already found lasting comfort with Dermeleve. Whether your itch stems from eczema, psoriasis, or everyday dryness, our formula delivers visible, lasting improvement without the risks of steroids or harsh chemicals.

Live without itch. Feel confident in your skin again with Dermeleve.

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