Live Without Itch

The #1 steroid-free solution developed by dermatologists to stop itch in 5 minutes.

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Science-Backed Ingredients

Developed by dermatologists for fast, 100% steroid-free relief, our skin-healing ingredients are backed by science.

SrX-38™

Targets the nerves to suppress the sensation of itch.

Ceramides

Lipid-rich molecules that retain moisture and promote skin regeneration.

Hyaluronic acid

Increases skin hydration up to 96% and helps heal skin more quickly.

Vitamins C & E

Antioxidants that help repair and protect skin from damage.

Say goodbye to itch for good!

Our maximum strength steroid-free formula is clinically proven to relieve itch at the source, moisturize, and promote healing.

100% steroid-free

Soothes and moisturizes

Eliminates itch in minutes

Safe for all skin types & ages

Product Image

Provides relief for up to 8 hours

Hypoallergenic

Helps promote healing

Fragrance free

Find the best-selling cream in Bundles

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2 oz. Cream Single Tube

2 oz. Cream Single Tube

Our best-selling steroid-free formula! Developed by dermatologists to relieve dry, itchy skin and...

$24.99

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4 oz. Cream Single Tube

4 oz. Cream Single Tube

Our advanced steroid-free formula in a large 4 ounce tube for maximum relief! Developed by dermat...

$39.99

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Scalp Serum Single Bottle

Scalp Serum Single Bottle

Heal your itchy, flaky scalp for good! Our maximum strength steroid-free formula is developed by ...

$24.99

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Itch-Free Duo

Itch-Free Duo

Banish itch from head to toe! Our best-selling 2oz. Dermeleve® cream relieves itchy, irritated sk...

$47.48

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Back Itch Bundle

Back Itch Bundle

Say goodbye to back itch with a large 4 oz. tube of our bestselling steroid-free formula, plus a ...

$43.99

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Scalp Brush

Scalp Brush

Level up your scalp care routine! Our new silicone Scalp Brush is designed to help exfoliate, mas...

$10.99

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Foldable Back Applicator

Foldable Back Applicator

Applying Dermeleve® cream has never been easier with our new Back Applicator! This handy device p...

$10.99

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Scalp Serum 2 Pack

Scalp Serum 2 Pack

Heal your itchy, flaky scalp for good! Our maximum strength steroid-free formula is developed by ...

$47.48

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The Proof is in the Experience

"I have had this itchy psoriasis on my hands for years! I have tried everything, including steroid ointments, (that I don’t want to use). My doctor recommended I try Dermeleve and my itching was gone within minutes, This is THE miracle cure."

Taylor R.

"Nothing helped with my chronic itching until I tried this cream. Seriously... the itching is almost completely gone after 5 years. I've been buying tubes for all my friends and family. Best product EVER!"

Theresa A.

"I have seborrheic dermatitis and have tried everything, from topical steroids to prescriptions. Nothing worked until I found Dermeleve. In a matter of minutes, my scalp itch was completely gone and I had no urge to scratch the rest of the day. I use this religiously every morning and will never go without it."

Cindy A.

"I have had this itchy psoriasis on my hands for years! I have tried everything, including steroid ointments, (that I don’t want to use). My doctor recommended I try Dermeleve and my itching was gone within minutes, This is THE miracle cure."

Taylor R.

"Nothing helped with my chronic itching until I tried this cream. Seriously... the itching is almost completely gone after 5 years. I've been buying tubes for all my friends and family. Best product EVER!"

Theresa A.

"I have seborrheic dermatitis and have tried everything, from topical steroids to prescriptions. Nothing worked until I found Dermeleve. In a matter of minutes, my scalp itch was completely gone and I had no urge to scratch the rest of the day. I use this religiously every morning and will never go without it."

Cindy A.