The science behind Dermeleve®
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The itch cycle
When itching is triggered either by external stimuli or internal conditions, it triggers an urge to scratch, which in turn results in inflammatory response and skin damage.
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The solution
Dermeleve® was specifically developed by dermatologists to target and reduce the sensation of itch, interrupting this vicious cycle and allowing skin to heal.
Skin healing ingredients
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SrX-38™
Made with strontium mineral salt, clinically proven to suppress sensory irritation and histamine-induced itch.
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Ceramides
Lipid-rich molecules that retain moisture and promote skin regeneration.
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Hyaluronic acid
Hyaluronic acid Increases skin hydration up to 96% and helps heal skin more quickly.
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Vitamins C & E
Antioxidants that help repair and protect skin from damage.
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Shea Butter
Smoothes dry skin while reducing swelling associated with skin conditions.
Hear from Dr. Dasilva

Dermeleve has been a game changer for me in many different itching disorders."

The proof is in the experience
Hear what patients and doctors have to say about Dermeleve®
FAQ

Dermeleve® is safe to be reapplied as needed throughout the day.

Dermeleve® can be used by anyone over the age of two suffering from irritation associated with itching, burning or stinging skin. For children under two check with your doctor to see if Dermeleve® is appropriate.

Yes. Dermeleve® does not thin the skin like steroid products can and is safe for use on sensitive skin.

- Active ingredient: aluminum acetate 0.2%
- Inactive Ingredients: Water, Strontium Nitrate, Isopropyl Myristate, Butyrospermum Parkii (shea) Butter, Caprylic/Capric Triglyceride, Cetearyl Alcohol Water, Strontium Nitrate, Isopropyl Myristate, Butyrospermum Parkii (shea) Butter, Caprylic/Capric Triglyceride, Cetearyl Alcohol, Emulsifying Wax NF, Glycerin, Phenoxyethanol, Magnesium Aluminum Silicate, Glyceryl Stearate, Dimethicone, Polyacrylate Crosspolymer-6, Xanthan Gum, Caprylyl Glycol, Sodium Hyaluronate (Hyaluronic Acid), Disodium EDTA, Ceramide NG, Tocopherol (Vitamin E), Tetrahexyldecyl Ascorbate

Yes, Dermeleve® is free of hydrocortisone and/or any other steroid. Many itch relief products are steroid-based and may contribute to unwanted side effects such as skin thinning, stretch marks, increased bruising, enlarged blood vessels and more. Dermeleve®’s unique, patented formula was developed to outperform other itch-relief products without the use of steroids.

No, our products are never tested on animals.

We stand by all of our products with a 100% satisfaction guarantee. So give Dermeleve® a try! If you are unhappy with your purchase for any reason, we will issue a full refund within thirty (30) days of purchase. No questions asked. Just contact our customer service department at support@dermeleve.com or call 877-684-2299. Once your refund is approved and we receive your remaining product back, we will issue your refund. (Return postage will not be covered).

Aluminum acetate is a water-soluble salt compound often used in medicine as an astringent or antiseptic. Dermeleve®’s patented formula works with the aluminum acetate to relieve itch and skin irritations. Aluminum Acetate is regulated by the Over-the-Counter (OTC) FDA monograph which describes aluminum-containing topical products used to treat minor skin irritations. These include:
- Insect bites and stings
- Itchy rashes from soaps, detergents, cosmetics and jewelry
- Poison ivy, oak and sumac
Aluminum is found naturally in the human diet in small amounts. According to this article on www.healthfully.com https://healthfully.com/aluminum-in-your-diet-7054020.html. "Beef, poultry, ham, eggs and fresh fruits have 1 milligram or less of aluminum per kilogram of food, according to a report from the Centers for Disease Control and Prevention. The aluminum in different types of fish ranges between 0.1 and 6 milligrams per kilogram. Most fresh vegetables contain 1 to 4 milligrams per kilogram, except for spinach, which has five times more. Tea leaves are one of the rare plants with a very high aluminum content, but not all of it leaches into the water when you prepare a cup of tea. You may get as much as 3.6 milligrams of aluminum per liter of steeped tea. This is about the same amount as fruit juice, but it’s four times higher than coffee and other beverages.
Aluminum is also used in many antiperspirants at concentrations upwards of 16%, and The National Cancer Institute’s webpage (https://www.cancer.gov/about-cancer/causes-prevention/risk/myths/antiperspirants-fact-sheet#what-is-known-about-the-relationship-between-antiperspirants-or-deodorants-and-breast-cancer) states that “no scientific evidence links the use of [antiperspirants] to the development of breast cancer.” Dermeleve® contains 0.2% Aluminum Acetate. This is 80 to 100 times less than standard anti-perspirants on the market.
In a preliminary study of the dermal absorption of aluminum from antiperspirants using aluminum-26 (https://pubmed.ncbi.nlm.nih.gov/11267710/), “Results indicate that only 0.012% of the applied aluminum was absorbed through the skin. At this rate, about 4 microg of aluminum is absorbed from a single use of ACH on both underarms. This is about 2.5% of the aluminum typically absorbed by the gut from food over the same time period. Therefore, a one-time use of ACH applied to the skin is not a significant contribution to the body burden of aluminum.”
Additional resources on Aluminum: No, you shouldn’t worry about aluminum in your antiperspirant https://wexnermedical.osu.edu/blog/aluminum-deoderantCancer.org: “Antiperspirants and Breast Cancer Risk“ https://www.cancer.org/content/dam/CRC/PDF/Public/6148.00.pdf Assessment of Dermal Absorption of Aluminum from a Representative Antiperspirant Formulation Using a 26Al Microtracer Approach https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226111/